An Anaplastic Astrocytoma is a malignant type of astrocytoma (Grade 3 astrocytoma).  We have a multidisciplinary team approach to offer state-of-the-art treatment regimens of both standard and experimental treatments.


  • Symptoms may include seizure, focal neurologic deficit (weakness or speech problems), headaches, personality changes, or visual loss.




  • Magnetic resonance imaging (MRI) is the preferred imaging technique for diagnosis.
  • An actual tissue biopsy is typically required for definitive diagnosis.


  • Surgery
  • If possible, we attempt to remove all of the tumor visible on the MRI to relieve pressure on the surrounding brain and improve the effectiveness of certain follow-up therapies.
    Advanced technologies such as Neuronavigation surgery and functional brain mapping available with us to  help improve surgical outcome.
  • Radiation therapy



    • Six weeks of radiation therapy usually follows surgery.
    • Gamma knife (stereotactic radiosurgery) has not been shown to be effective for anaplastic astrocytoma.
    • Stereotactic radiotherapy (using the True Beam) may be offered in certain circumstances.
  • Chemotherapy
  • Standard oral chemotherapy, such as temozolomide (Temoget), is generally given during the radiation treatment with additional doses afterward.
    • Wafers loaded with chemotherapy (Gliadel) can be placed at the time of surgery. Ask your neurosurgeon and/or neuro-oncologist about this prior to surgery.
  • Clinical research trials
    • We offer many of the latest multicenter clinical trials available for anaplastic astrocytoma.